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butabarbital will reduce the level or result of levonorgestrel oral/ethinylestradiol/ferrous bisglycinate by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Check Intently. The efficacy of hormonal contraceptives can be minimized.butabarbital will reduce the level or effect of fosphenytoin by influencing hepatic enzyme CYP2C